Stephen B Kritchevsky Selected Research

Idiopathic Pulmonary Fibrosis

3/2022	Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans.
2/2019	Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study.

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Stephen B Kritchevsky Research Topics

Disease

30	Inflammation (Inflammations) 12/2020 - 05/2002
20	Cardiovascular Diseases (Cardiovascular Disease) 10/2022 - 03/2003
20	Heart Failure 01/2022 - 09/2003
14	Weight Loss (Weight Reduction) 05/2024 - 08/2004
14	Chronic Disease (Chronic Diseases) 07/2023 - 10/2011
13	Frailty 04/2024 - 01/2016
13	Hypertension (High Blood Pressure) 10/2022 - 05/2002
12	Obesity 09/2023 - 08/2005
11	Type 2 Diabetes Mellitus (MODY) 01/2023 - 09/2005
11	Mobility Limitation (Difficulty Walking) 01/2021 - 07/2004
10	Body Weight (Weight, Body) 02/2024 - 07/2008
8	Diabetes Mellitus 04/2024 - 06/2007
8	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 04/2004
7	Sarcopenia 10/2023 - 08/2005
7	Cognitive Dysfunction 01/2021 - 06/2006
7	Coronary Disease (Coronary Heart Disease) 01/2016 - 08/2003
6	Chronic Renal Insufficiency 04/2024 - 10/2014
6	Overweight 10/2022 - 08/2011
6	Insulin Resistance 04/2021 - 07/2009
6	Stroke (Strokes) 01/2016 - 07/2002
5	Atherosclerosis 01/2020 - 05/2009
4	Osteoarthritis 01/2020 - 03/2017
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020 - 10/2011
4	Kidney Diseases (Kidney Disease) 01/2016 - 07/2011
3	Chronic Obstructive Pulmonary Disease (COPD) 04/2024 - 09/2012
3	Dementia (Dementias) 03/2024 - 07/2009
3	Coronary Artery Disease (Coronary Atherosclerosis) 03/2017 - 09/2003
3	Pain (Aches) 01/2017 - 11/2004
3	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 01/2015 - 07/2008
3	Pneumonia (Pneumonitis) 09/2013 - 12/2005
3	Vitamin D Deficiency 10/2011 - 04/2007
3	Infections 07/2009 - 01/2006
3	Sepsis (Septicemia) 01/2008 - 12/2003
3	Myocardial Infarction 12/2006 - 04/2004
2	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 06/2006
2	Idiopathic Pulmonary Fibrosis 03/2022 - 02/2019
2	Urinary Incontinence 01/2022 - 11/2017
2	Osteoporosis 11/2021 - 11/2005
2	Hyperglycemia 04/2021 - 08/2006
2	Bone Diseases (Bone Disease) 01/2020 - 07/2012
2	Knee Osteoarthritis 01/2018 - 11/2004
2	Glucose Intolerance 05/2015 - 08/2006
2	Macular Degeneration (Age-Related Maculopathy) 01/2015 - 04/2007

Drug/Important Bio-Agent (IBA)

26	Interleukin-6 (Interleukin 6)IBA 10/2022 - 09/2003
20	Biomarkers (Surrogate Marker)IBA 09/2023 - 11/2008
17	C-Reactive ProteinIBA 10/2022 - 09/2003
13	Proteins (Proteins, Gene)FDA Link 03/2024 - 09/2005
11	Glucose (Dextrose)FDA LinkGeneric 01/2017 - 08/2006
11	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2014 - 09/2003
10	Vitamin D FDA LinkGeneric 01/2020 - 10/2003
9	25-hydroxyvitamin DIBA 01/2023 - 04/2011
8	hydroxide ionIBA 01/2023 - 04/2011
8	Vitamin K FDA Link 01/2020 - 08/2011
7	oxidized low density lipoproteinIBA 02/2011 - 03/2003
6	CreatinineIBA 03/2022 - 01/2008
6	Plasminogen Activator Inhibitor 1IBA 05/2009 - 08/2005
5	Triglycerides (Triacylglycerol)IBA 04/2021 - 05/2007
5	InterleukinsIBA 09/2020 - 09/2003
5	Antihypertensive Agents (Antihypertensives)IBA 08/2011 - 07/2002
5	HDL CholesterolIBA 02/2011 - 02/2004
4	CarbohydratesIBA 04/2024 - 09/2005
4	Indicators and Reagents (Reagents)IBA 04/2021 - 11/2003
4	Vitamin K 1 (Phylloquinone)FDA LinkGeneric 01/2020 - 07/2013
4	CholesterolIBA 01/2017 - 04/2004
4	AdiponectinIBA 02/2016 - 04/2008
4	AlbuminsIBA 03/2015 - 09/2005
4	AdipokinesIBA 09/2012 - 04/2008
4	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 07/2009 - 07/2002
3	Metformin (Glucophage)FDA LinkGeneric 01/2023 - 12/2018
3	Cystatin CIBA 03/2022 - 07/2006
3	Dietary ProteinsIBA 01/2020 - 01/2008
3	Blood Glucose (Blood Sugar)IBA 04/2017 - 08/2010
3	Hemoglobins (Hemoglobin)IBA 01/2017 - 05/2013
3	Insulin (Novolin)FDA Link 02/2016 - 09/2009
3	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2014 - 09/2003
3	CalciumIBA 07/2013 - 10/2003
3	CytokinesIBA 09/2009 - 09/2003
2	Fatty Acids (Saturated Fatty Acids)IBA 04/2024 - 04/2021
2	Clostridium perfringens epsilon-toxinIBA 04/2024 - 09/2023
2	Muscle Proteins (Muscle Protein)IBA 02/2024 - 11/2023
2	CreatineIBA 10/2023 - 10/2023
2	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2023 - 06/2007
2	SenotherapeuticsIBA 11/2021 - 02/2019
2	Hypoglycemic Agents (Hypoglycemics)IBA 01/2020 - 01/2009
2	MucinsIBA 01/2020 - 01/2020
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017 - 02/2004
2	ResistinIBA 02/2016 - 07/2009
2	LeptinIBA 02/2016 - 04/2008
2	Dietary SodiumIBA 09/2015 - 03/2015
2	AntioxidantsIBA 10/2013 - 03/2006
2	Pioglitazone (Actos)FDA Link 07/2013 - 08/2011
2	Parathyroid Hormone (Parathormone)IBA 02/2013 - 11/2008
2	MineralsIBA 07/2012 - 07/2011

Therapy/Procedure

8	Caloric Restriction 09/2023 - 07/2008
4	Therapeutics 05/2024 - 01/2020
4	Resistance Training 05/2024 - 08/2011
4	Activities of Daily Living (ADL) 11/2011 - 07/2009
2	Length of Stay 01/2018 - 04/2006
2	Drug Therapy (Chemotherapy) 10/2016 - 10/2011
2	Induction Chemotherapy 05/2013 - 10/2011